It would be great to have two different notification profiles for a monitor, and the ability to tie those alerts to different alert groups, severity or custom schedules.

For my first example, I may have a web server.  I would like to receive an email notification if a monitor is unable to get to the site on the first attempt.  If there are 2 more (total of 3 polls) and the site is still down, I then would like to receive a page, or notify a different alert group.

Another example of this is that from 7AM-6PM Mon-Fri I want a page notification if a particular monitor goes off just once.  The rest of the time, evenings and weekends, I may only want an email notification after 3 instances of the monitor triggering.   

Last example is that perhaps I want email notifications for trouble events, and want pages for down events, or one alert group for trouble and another alert group for down events.